Company Overview

CRISPR Therapeutics is a leading gene editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations in Boston, Massachusetts and San Francisco, California, and business offices in London, United Kingdom.

Position Summary

The Scientist will be leading our efforts in the design and synthesis of novel chemical compounds to help advance our non-viral delivery platform. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team of LNP delivery chemistry scientists.

Responsibilities

• Design, synthesize, and purify novel chemical compounds including, but not limited to- lipids, polymers, or bioconjugates with minimal supervision
• Plan and execute multistep synthesis for the preparation of novel chemical compounds
• Work closely with analytical and formulation scientists to characterize and evaluate compounds for delivery systems; analyze structure activity relationships (SAR) of the compounds and apply new learnings in new designs
• Collaborate with IP counsels to support CRISPR Therapeutics patent applications and prosecutions
• Utilize scientific database to stay up to date on published delivery chemistry literature

Minimum Qualifications

• Ph.D. in Organic Chemistry or related field, or a M.S./B.S. degree in Chemistry with 6+ years of relevant industry experience
• Excellent technical skills in synthetic chemistry in addition to proficiency with multi-step chemical synthesis
• Hands on experience with NMR, MS, HPLC, TLC, and other common analytical methods
• Pays great attention to details in the quality of the synthesized chemical compounds
• Strong written and oral communication skills
• A team player with strong interpersonal skills, and ability to collaborate effectively with others

Preferred Qualifications

• Industry experience in medicinal chemistry
• Industry experience in lipid chemistry or conjugation chemistries for drug delivery

Competencies

• Collaborative – Openness, One Team
• Undaunted – Fearless, Can-do attitude
• Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
• Entrepreneurial Spirit – Proactive. Ownership mindset.

CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.

To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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